Bordetella Pertussis virulence factors in the continuing evolution of whooping cough vaccines for improved performance

@article{Dorji2017BordetellaPV,
  title={Bordetella Pertussis virulence factors in the continuing evolution of whooping cough vaccines for improved performance},
  author={Dorji Dorji and Frits R. Mooi and Osvaldo M Yantorno and Rajendar Deora and Ross M. Graham and Trilochan K S Mukkur},
  journal={Medical Microbiology and Immunology},
  year={2017},
  volume={207},
  pages={3-26}
}
Despite high vaccine coverage, whooping cough caused by Bordetella pertussis remains one of the most common vaccine-preventable diseases worldwide. Introduction of whole-cell pertussis (wP) vaccines in the 1940s and acellular pertussis (aP) vaccines in 1990s reduced the mortality due to pertussis. Despite induction of both antibody and cell-mediated immune (CMI) responses by aP and wP vaccines, there has been resurgence of pertussis in many countries in recent years. Possible reasons… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS
5 Extracted Citations
210 Extracted References
Similar Papers

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 210 references

Investigations into the emergence of pertactin-deficient Bordetella pertussis isolates

  • A Zeddeman, M van Gent, CJ Heuvelman
  • in six European countries,
  • 2014
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…