Borapetoside E, a Clerodane Diterpenoid Extracted from Tinospora crispa, Improves Hyperglycemia and Hyperlipidemia in High-Fat-Diet-Induced Type 2 Diabetes Mice.

@article{Xu2017BorapetosideEA,
  title={Borapetoside E, a Clerodane Diterpenoid Extracted from Tinospora crispa, Improves Hyperglycemia and Hyperlipidemia in High-Fat-Diet-Induced Type 2 Diabetes Mice.},
  author={Yuhui Xu and Yan-fen Niu and Yuan Gao and Fang Wang and Wanying Qin and Yanting Lu and Jing Hu and Li Peng and Jikai Liu and Wenyong Xiong},
  journal={Journal of natural products},
  year={2017},
  volume={80 8},
  pages={
          2319-2327
        }
}
An insidious increase in the incidence of obesity, insulin resistance, and hyperlipidemia has led to an epidemic of type 2 diabetes worldwide. Tinospora crispa (T. crispa) is a familiar plant traditionally used in herbal medicine for diabetes; however, the major active ingredients of this plant are still unclear. In this study, we identified the therapeutic effects of borapetoside E, a small molecule extracted from T. crispa, in high-fat-diet (HFD)-induced obesity in mice. The therapeutic… 

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