Boost of CD34+-selected peripheral blood cells without further conditioning in patients with poor graft function following allogeneic stem cell transplantation.

@article{Larocca2006BoostOC,
  title={Boost of CD34+-selected peripheral blood cells without further conditioning in patients with poor graft function following allogeneic stem cell transplantation.},
  author={Alessandra Larocca and Giovanna Piaggio and Marina Podest{\`a} and Anna Pitto and Barbara Bruno and Carmen Di Grazia and Francesca Gualandi and Domenico Occhini and Anna Maria Raiola and Alida Dominietto and Stefania Bregante and Teresa Lamparelli and Elisabetta Tedone and R. A. B. Oneto and Francesco Frassoni and Maria Teresa Van Lint and Enrico Maria Pogliani and Andrea Bacigalupo},
  journal={Haematologica},
  year={2006},
  volume={91 7},
  pages={935-40}
}
BACKGROUND AND OBJECTIVES A proportion of patients develop poor graft function (PGF) following an allogeneic hemopoietic stem cell transplant (HSCT). It is uncertain whether a boost of donor marrow or blood cells is beneficial in terms of trilineage recovery and non-relapse-related mortality (NRM). DESIGN AND METHODS The aim of this study was to compare outcomes in patients with PGF and full donor chimerism following an allogeneic HSCT who did or did not receive a boost of donor stem cells… CONTINUE READING

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Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation • 2017
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Fresh or Cryopreserved CD34+-Selected Mobilized Peripheral Blood Stem and Progenitor Cells for the Treatment of Poor Graft Function after Allogeneic Hematopoietic Cell Transplantation.

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T Cell-Mediated Rejection of Human CD34+ Cells Is Prevented by Costimulatory Blockade in a Xenograft Model.

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