Boolean modeling of transcriptome data reveals novel modes of heterotrimeric G-protein action

@inproceedings{Pandey2010BooleanMO,
  title={Boolean modeling of transcriptome data reveals novel modes of heterotrimeric G-protein action},
  author={Sona Pandey and Rebecca Wang and Liza Wilson and Song Li and Zhixin Zhao and Timothy E Gookin and Sarah M. Assmann and R{\'e}ka Albert},
  booktitle={Molecular systems biology},
  year={2010}
}
Heterotrimeric G-proteins mediate crucial and diverse signaling pathways in eukaryotes. Here, we generate and analyze microarray data from guard cells and leaves of G-protein subunit mutants of the model plant Arabidopsis thaliana, with or without treatment with the stress hormone, abscisic acid. Although G-protein control of the transcriptome has received little attention to date in any system, transcriptome analysis allows us to search for potentially uncommon yet significant signaling… CONTINUE READING

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Systems biology approaches to abscisic acid signaling

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