Bone substitute biomedical material of multi-(amino acid) copolymer: in vitro degradation and biocompatibility.

@article{Li2011BoneSB,
  title={Bone substitute biomedical material of multi-(amino acid) copolymer: in vitro degradation and biocompatibility.},
  author={Hong Li and Yonggang Yan and Jie Wei and Jian Ma and Min Gong and Xiaoman Luo and Yunfei Zhang},
  journal={Journal of materials science. Materials in medicine},
  year={2011},
  volume={22 11},
  pages={2555-63}
}
Degradable polymers with good mechanical strength as bone repair biomaterials have been paid more attention in biomedical application. In this study, a multi-(amino acid) copolymer consisting of 6-aminocaproic acid and five natural amino acids was prepared by a reaction of acid-catalyzed condensation. The results revealed that the copolymer could be slowly degradable in Tris-HCl solution, and lost its initial weight of 31.9 wt% after immersion for 12 weeks, and the changes of pH value of Tris… CONTINUE READING
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