Bone morphogenic proteins signaling in adipogenesis and energy homeostasis.

  title={Bone morphogenic proteins signaling in adipogenesis and energy homeostasis.},
  author={Salvatore Modica and Christian Wolfrum},
  journal={Biochimica et biophysica acta},
  volume={1831 5},
A great deal is known about the molecular mechanisms regulating terminal differentiation of pre-adipocytes into mature adipocytes. In contrast, the knowledge about pathways that trigger commitment of mesenchymal stem cells into the adipocyte lineage is fragmented. In recent years, the role of members of the bone morphogenic protein family in regulating the early steps of adipogenesis has been the focus of research. Findings based on these studies have also highlighted an unexpected role for… CONTINUE READING
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