Bone morphogenetic protein signaling promotes tumorigenesis in a murine model of high-grade glioma.

Abstract

BACKGROUND Improved therapies for high-grade glioma (HGG) are urgently needed as the median survival for grade IV gliomas is only 15 months. Bone morphogenetic protein (BMP) signaling plays critical and complex roles in many types of cancer, including glioma, with most of the recently published work focusing on BMP-mediated regulation of glioma stem cells… (More)
DOI: 10.1093/neuonc/nov310

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.

Slides referencing similar topics