Bone morphogenetic protein and orthopaedic surgery: Can we legitimate its off-label use?

@article{Courvoisier2014BoneMP,
  title={Bone morphogenetic protein and orthopaedic surgery: Can we legitimate its off-label use?},
  author={Aur{\'e}lien Courvoisier and Fr{\'e}d{\'e}ric Sailhan and Olivier Laffen{\^e}tre and Laurent Obert},
  journal={International Orthopaedics},
  year={2014},
  volume={38},
  pages={2601-2605}
}
Bone morphogenetic proteins (BMP) are recombinant osteoinductive proteins with their primary role being to promote bone formation. The off-label use of BMP in orthopaedic surgery has dramatically increased. However, reports of complications with BMP have emerged, and the safety of these proteins in orthopaedics is questioned. The purpose of this review was… CONTINUE READING