Bone morphogenetic protein-4 inhibits heat-induced apoptosis by modulating MAPK pathways in human colon cancer HCT116 cells.

@article{Deng2007BoneMP,
  title={Bone morphogenetic protein-4 inhibits heat-induced apoptosis by modulating MAPK pathways in human colon cancer HCT116 cells.},
  author={Haiyun Deng and Thanjavur S. Ravikumar and W L Yang},
  journal={Cancer letters},
  year={2007},
  volume={256 2},
  pages={207-17}
}
Cancer thermotherapy and radiofrequency ablation (RFA) have been adopted as modalities for treating various kinds of cancer. We have previously demonstrated that bone morphogenetic protein-4 (BMP-4) is up-regulated in colonic adenocarcinoma. Here, we investigated whether an increase of BMP-4 expression changes cellular response to heat treatment in human… CONTINUE READING