Bone morphogenetic protein 2 therapy for craniofacial surgery.

@article{Smith2008BoneMP,
  title={Bone morphogenetic protein 2 therapy for craniofacial surgery.},
  author={Daniel Preston Smith and Gregory M. Cooper and Mark Patrick Mooney and Kacey G Marra and Joseph E. Losee},
  journal={The Journal of craniofacial surgery},
  year={2008},
  volume={19 5},
  pages={
          1244-59
        }
}
Between 2 and 10 years of age, the developing craniofacial skeleton poses a significant reconstructive challenge. Local autogenous bone is largely unavailable, distant bone grafts are fraught with significant morbidity and limited yield, and alloplastic materials are incompatible with the growing calvarium and facial skeleton. Bone morphogenetic protein (BMP) 2, a member of a class of proteins first noticed in the 1960s to promote bone deposition in soft tissues, offers a potential solution to… CONTINUE READING
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