Bone mineral density in children with sickle cell anemia.

  title={Bone mineral density in children with sickle cell anemia.},
  author={Ashutosh Lal and Ellen B. Fung and Zahra Pakbaz and Ekua Hackney-Stephens and Elliott Vichinsky},
  journal={Pediatric blood & cancer},
  volume={47 7},
PURPOSE We evaluated bone mineral density (BMD) and risk factors for poor bone mineralization in children with sickle cell anemia (SCA). PATIENTS AND METHODS Twenty-five children with severe manifestations of SCA (frequent hospitalizations, growth delay, or need for chronic red cell transfusions) were enrolled. Bone density was assessed at lumbar spine and proximal femur with dual-energy X-ray absorptiometry (DXA), and Z-scores were calculated by comparison with age, sex, and ethnicity… CONTINUE READING
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