Bone mineral density and bone turnover in asthmatics treated with long-term inhaled or oral glucocorticoids.

@article{Ebeling1998BoneMD,
  title={Bone mineral density and bone turnover in asthmatics treated with long-term inhaled or oral glucocorticoids.},
  author={Peter R. Ebeling and Belkis Erbas and John L. Hopper and John Dennis Wark and Abe R Rubinfeld},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={1998},
  volume={13 8},
  pages={1283-9}
}
Inhaled glucocorticoids are pivotal in maintenance therapy of chronic bronchial asthma; however, conflict exists over their effects on bone and mineral metabolism. We measured bone mineral density (BMD), bone turnover markers, and adrenal steroid hormones in 53 patients (34 female, 19 male) with chronic bronchial asthma who had taken either inhaled beclomethasone or budesonide in doses of > or = 1500 microg/day for at least 12 months to determine pathogenetic mechanisms of bone loss. To account… CONTINUE READING
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