Bone metastasis: pathogenesis and therapeutic implications

  title={Bone metastasis: pathogenesis and therapeutic implications},
  author={Philippe Cl{\'e}zardin and Anna Maria Teti},
  journal={Clinical & Experimental Metastasis},
Advanced cancers are prone to metastasize. Visceral metastases are more likely to be fatal, while patients with only metastases to bone can survive up to 10 years or more. However, effective treatments for bone metastases are not yet available and bisphosphonates improve the quality of life with no life-prolonging benefits. Bone metastases are classified as osteolytic, osteosclerotic or mixed lesions according to the bone cell types more prominently involved. Either conditions induce high… CONTINUE READING
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Bone metastases

  • CG Wilfred, M Muttarak
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  • 2007
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