Bone matrix turnover and balance in vitro. I. The effects of parathyroid hormone and thyrocalcitonin.

Abstract

Labeled proline from incubation media has been shown to be incorporated into living bone matrix collagen in vitro. Hydroxyproline is released from fresh bone slices in similar systems in a characteristic curve against time. This hydroxyproline is derived from three distinct sources, each of which may be separately quantitated. Part of the total represents… (More)

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