Bone mass in androgen-insensitivity syndrome: Response to hormonal replacement therapy

  title={Bone mass in androgen-insensitivity syndrome: Response to hormonal replacement therapy},
  author={M. Mu{\~n}oz-Torres and E. J{\'o}dar and M. Quesada and F. Escobar-Jim{\'e}nez},
  journal={Calcified Tissue International},
  • M. Muñoz-Torres, E. Jódar, +1 author F. Escobar-Jiménez
  • Published 2004
  • Chemistry, Medicine
  • Calcified Tissue International
  • The response of bone mass to long-term treatment with estrogen and progesterone in patients with complete androgen-insensitivity syndrome (AIS) is unknown. We report a 17-year-old female patient (karyotype 46 X, Y) with AIS studied during a 4-year period. Bone mineral density (BMD) measured by dual X-ray absorptiometry in lumbar spine and proximal femur was sharply reduced at the initial visit, and remained unchanged during long-term follow-up on hormone replacement therapy with estrogens and… CONTINUE READING
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