Bone marrow transplantation of chronic myelogenous leukemia in chronic phase: evaluation of risks and benefits.

@article{Wagner1992BoneMT,
  title={Bone marrow transplantation of chronic myelogenous leukemia in chronic phase: evaluation of risks and benefits.},
  author={John E Wagner and Marriana Zahurak and Steve Piantadosi and Robert B. Geller and Georgia B. Vogelsang and John R Wingard and Rein Saral and C. F. Griffin and Neha Shah and Barbara A. Zehnbauer},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={1992},
  volume={10 5},
  pages={779-89}
}
PURPOSE Allogeneic bone marrow transplantation (BMT) is an option for some patients with chronic myelogenous leukemia (CML). We retrospectively evaluated the effect of various risk factors observed at diagnosis and at transplantation on survival, event-free survival (EFS), and relapse after BMT. PATIENTS AND METHODS Seventy-nine patients with CML in chronic phase (CP) were treated with cyclophosphamide and total body irradiation followed by BMT. Graft-versus-host disease (GVHD) prophylaxis… CONTINUE READING
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