Bone marrow transplantation in patients with thalassemia.

  title={Bone marrow transplantation in patients with thalassemia.},
  author={G. Lucarelli and M. C. Galimberti and Paola Polchi and Emanuele Angelucci and Donatella Baronciani and Claudio Giardini and Peirluigi Politi and S M Durazzi and Pietro Muretto and Francesca Albertini},
  journal={The New England journal of medicine},
  volume={322 7},
We reviewed the results of transplantation of allogeneic marrow from HLA-identical donors in patients with beta-thalassemia who were less than 16 years old. Among the 222 consecutive patients who had received transplants since 1983, survival and event-free-survival curves leveled off about one year after transplantation, at 82 and 75 percent, respectively. Pretransplantation clinical characteristics were examined for their impact on survival, event-free survival, and the recurrence of… CONTINUE READING
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