Bone marrow transplantation for severe aplastic anemia from genotypically HLA-nonidentical relatives. An update of the Seattle experience.

@article{Wagner1996BoneMT,
  title={Bone marrow transplantation for severe aplastic anemia from genotypically HLA-nonidentical relatives. An update of the Seattle experience.},
  author={John L. Wagner and H. Joachim Deeg and Kristy Seidel and Claudio Anasetti and Kristine C Doney and Jean E. Sanders and Keith M. Sullivan and Rainer F Storb},
  journal={Transplantation},
  year={1996},
  volume={61 1},
  pages={54-61}
}
This report updates the results of marrow transplantation at the Fred Hutchinson Cancer Research Center for patients with severe aplastic anemia whose donors were HLA-nonidentical relatives. Between 1970 and 1993, 40 patients received transplants for severe aplastic anemia from related donors other than HLA genotypically matched siblings. Nine patients (group 1) were conditioned with cyclophosphamide (Cy) at 50 mg/kg for 4 doses and received marrow from phenotypically HLA-matched relatives… CONTINUE READING