Bone marrow transplantation (BMT) versus immunosuppression for the treatment of severe aplastic anaemia (SAA): a report of the EBMT SAA working party.

@article{Bacigalupo1988BoneMT,
  title={Bone marrow transplantation (BMT) versus immunosuppression for the treatment of severe aplastic anaemia (SAA): a report of the EBMT SAA working party.},
  author={Andrea A Bacigalupo and Jill M Hows and Eliane Gluckman and Catherine Nissen and Judith Marsh and Maria Teresa Van Lint and Margherita Congiu and M M de Planque and Peter Ernst and Shaun McCann},
  journal={British journal of haematology},
  year={1988},
  volume={70 2},
  pages={177-82}
}
This is an analysis of 509 patients with severe aplastic anaemia (SAA) treated in Europe between 1981 and 1986; 218 patients were treated by allogeneic bone marrow transplantation (BMT) from HLA identical sibling donors and 291 with immunosuppressive therapy (IS) with antilymphocyte globulin (ALG). The overall actuarial survival was 63% after BMT and 61% after IS therapy at 6 years. All patients fulfilled the criteria of SAA; however, most patients with a neutrophil count of less than 0.2 x 10… CONTINUE READING

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