Bone marrow stromal damage after chemo/radiotherapy: occurrence, consequences and possibilities of treatment.

@article{Banfi2001BoneMS,
  title={Bone marrow stromal damage after chemo/radiotherapy: occurrence, consequences and possibilities of treatment.},
  author={Andrea Banfi and Giada Bianchi and M Galotto and Ranieri Cancedda and Rodolfo Quarto},
  journal={Leukemia & lymphoma},
  year={2001},
  volume={42 5},
  pages={863-70}
}
High dose chemotherapy (CT) followed by bone marrow transplant (BMT) is increasingly used for the treatment of both hematological and solid neoplasms, but an understanding of its late consequences on the marrow microenvironment is still only at its beginning. It is in fact known that marrow stroma is damaged by high-dose cytotoxic therapy and by radiation exposure. However little is known on the extent of this damage and on the self-repair ability of the stroma. The damage of the stromal… CONTINUE READING
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