Bone marrow stromal cells from myeloma patients support the growth of myeloma stem cells.

@article{Feng2010BoneMS,
  title={Bone marrow stromal cells from myeloma patients support the growth of myeloma stem cells.},
  author={Yongdong Feng and Jianguo Wen and P. Murtaugh Mike and Dong Soon Choi and Camellia Eshoa and Zheng-zheng Shi and Youli Zu and Chung-che Chang},
  journal={Stem cells and development},
  year={2010},
  volume={19 9},
  pages={
          1289-96
        }
}
It has been well documented that bone marrow stromal cells (BMSCs) of multiple myeloma patients play a pivotal role in supporting the growth of mature myeloma cells. With evolving concepts concerning the presence of myeloma stem (initiating) cells, we aimed this investigation to specifically address the supportive role of BMSCs for myeloma stem cell growth in vitro and in vivo. BMSC lines were derived from myeloma or control patients (myeloma or control BMSCs). Myeloma stem cells of the RPMI… CONTINUE READING
BETA

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 25 CITATIONS

E-cadherin expression on multiple myeloma cells activates tumor-promoting properties in plasmacytoid DCs.

Enguang Bi, Rong Li, +12 authors Qing Yi
  • The Journal of clinical investigation
  • 2018
VIEW 3 EXCERPTS
CITES BACKGROUND