Bone marrow stem cells in facial nerve regeneration from isolated stumps.

@article{Salomone2013BoneMS,
  title={Bone marrow stem cells in facial nerve regeneration from isolated stumps.},
  author={Raquel Salomone and Ricardo Ferreira Bento and Heloisa Juliana Zabeu Rossi Costa and Deborah Azzi-Nogueira and Patr{\'i}cia Camacho Ovando and Ciro Ferreira Da-Silva and Daniela Bertolini Zanatta and Bryan E Strauss and Luciana A. Haddad},
  journal={Muscle & nerve},
  year={2013},
  volume={48 3},
  pages={423-9}
}
INTRODUCTION Severe lesions in the facial nerve may have extensive axonal loss and leave isolated stumps that impose technical difficulties for nerve grafting. METHODS We evaluated bone marrow stem cells (BMSC) in a silicone conduit for rat facial nerve regeneration from isolated stumps. Group A utilized empty silicone tubes; in groups B-D, the tube was filled with acellular gel; and, in groups C and D, undifferentiated BMSC (uBMSC) or Schwann-like cells differentiated from BMSC (dBMSC) were… CONTINUE READING