Bone marrow-resident memory T cells survive pretransplant chemotherapy and contribute to early immune reconstitution of patients with acute myeloid leukemia given mafosfamide-purged autologous bone marrow transplantation.

@article{Casorati2005BoneMM,
  title={Bone marrow-resident memory T cells survive pretransplant chemotherapy and contribute to early immune reconstitution of patients with acute myeloid leukemia given mafosfamide-purged autologous bone marrow transplantation.},
  author={Giulia Casorati and Franco Locatelli and Sara Pagani and Claudio Garavaglia and Enrica Montini and Daniela Lisini and Ilaria Turin and Francesca Manes Rossi and Paolo Dellabona and Rita Maccario and Daniela Montagna},
  journal={Experimental hematology},
  year={2005},
  volume={33 2},
  pages={212-8}
}
OBJECTIVE Studies of memory T cells transferred with the graft are relevant to better understand the early immune reconstitution of patients given autologous bone marrow transplantation (A-BMT). A critical question is whether memory T cells resident in bone marrow (BM) of patients with hematological malignancies are resistant to either pretransplant chemotherapy or ex vivo pharmacological purging. PATIENTS AND METHODS To address these issues, we evaluated the frequency of tetanus-toxoid (TT… CONTINUE READING

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