Bone marrow monocyte lineage cells adhere on injured endothelium in a monocyte chemoattractant protein-1-dependent manner and accelerate reendothelialization as endothelial progenitor cells.

@article{Fujiyama2003BoneMM,
  title={Bone marrow monocyte lineage cells adhere on injured endothelium in a monocyte chemoattractant protein-1-dependent manner and accelerate reendothelialization as endothelial progenitor cells.},
  author={Soichiro Fujiyama and Katsuya Amano and Kazutaka Uehira and Masayuki Yoshida and Yasunobu Nishiwaki and Yoshihisa Nozawa and Denan Jin and Shinji Takai and Mizuo Miyazaki and Kensuke Egashira and Takayuki Imada and Toshiji Iwasaka and Hiroaki Matsubara},
  journal={Circulation research},
  year={2003},
  volume={93 10},
  pages={980-9}
}
Peripheral blood (PB)-derived CD14+ monocytes were shown to transdifferentiate into endothelial cell (EC) lineage cells and contribute to neovascularization. We investigated whether bone marrow (BM)- or PB-derived CD34-/CD14+ cells are involved in reendothelialization after carotid balloon injury. Although neither hematopoietic nor mesenchymal stem cells were included in human BM-derived CD34-/CD14+ monocyte lineage cells (BM-MLCs), they expressed EC-specific markers (Tie2, CD31, VE-cadherin… CONTINUE READING

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