Bone marrow mesenchymal stem cells reduce intestinal ischemia/reperfusion injuries in rats.

@article{Jiang2011BoneMM,
  title={Bone marrow mesenchymal stem cells reduce intestinal ischemia/reperfusion injuries in rats.},
  author={Haitao Jiang and Linlin Qu and Y. L. Li and Lili Gu and Yichao Shi and Jian Zhang and Weiming Zhu and Jie-shou Li},
  journal={The Journal of surgical research},
  year={2011},
  volume={168 1},
  pages={127-34}
}
BACKGROUND Adult stem cells are promising novel therapies in regenerative medicine. We investigated effects of bone marrow-derived mesenchymal stem cells (MSCs) on intestinal mucosal permeability impaired by ischemia/reperfusion (I/R). METHODS We used a common I/R model in rats to induce intestinal injury by clamping and unclamping the superior mesenteric artery (SMA) in female Sprague-Dawley rats. MSCs were directly injected into the small intestinal submucosa of the syngenic female rats… CONTINUE READING