Bone marrow mesenchymal stem cells in myelodysplastic syndromes: cytogenetic characterization.

@article{Song2012BoneMM,
  title={Bone marrow mesenchymal stem cells in myelodysplastic syndromes: cytogenetic characterization.},
  author={Lu-xi Song and Juan Guo and Qi He and Lian-Ping Yang and Shu-cheng Gu and Xiaoying Zhang and Ling-Yun Wu and Xiao Li and Chunkang Chang},
  journal={Acta haematologica},
  year={2012},
  volume={128 3},
  pages={170-7}
}
AIM This study compared genetic aberrations in hematopoietic cells (HCs) and mesenchymal stem cells of myelodysplastic syndrome (MDS-MSCs) patients. METHODS We obtained chromosomes with aberrations from 22 patients with MDS and chromosomes from 7 healthy individuals. Chromosomal aberrations in both HCs and MSCs were identified using G-banding. We then performed DNA content analysis of the HCs and MSCs. RESULTS Cytogenetic aberrations were detected in HCs from 13 of the 22 MDS patients (59… CONTINUE READING