Bone marrow-derived mesenchymal stromal cells accelerate wound healing in the rat.

  title={Bone marrow-derived mesenchymal stromal cells accelerate wound healing in the rat.},
  author={Kellie McFarlin and Xiaohua Gao and Yong Bo Liu and Deborah S Dulchavsky and David Kwon and Ali S. Arbab and Mona Bansal and Yi Li and Michael Chopp and Scott A. Dulchavsky and Subhash C. Gautam},
  journal={Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society},
  volume={14 4},
Bone marrow-derived mesenchymal stromal cells (BMSCs) are multipotential stem cells capable of differentiation into numerous cell types, including fibroblasts, cartilage, bone, muscle, and brain cells. BMSCs also secrete a large number of growth factors and cytokines that are critical to the repair of injured tissues. Because of the extraordinary plasticity and the ability of syngeneic or allogeneic BMSCs to secrete tissue-repair factors, we investigated the therapeutic efficacy of BMSCs for… CONTINUE READING
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