Bone marrow-derived mesenchymal stem cells reduce immune reaction in a mouse model of allergic rhinitis.

@article{Zhao2016BoneMM,
  title={Bone marrow-derived mesenchymal stem cells reduce immune reaction in a mouse model of allergic rhinitis.},
  author={Ning Zhao and Y Liu and Hongfeng Liang and Xuejun Jiang},
  journal={American journal of translational research},
  year={2016},
  volume={8 12},
  pages={5628-5636}
}
OBJECT To determine the potential of bone marrow-derived mesenchymal stem cells (BMSCs) for immunomodulatory mechanism in mice model of allergic rhinitis (AR). METHODS BMSCs were isolated and the surface markers and stemness were analyzed. The effect of BMSCs was evaluated in BALB/c mice that were randomly divided into three groups (control group, ovalbumin (OVA) group, OVA+BMSCs group). BMSCs were administered intravenously to OVA sensitized mice on days 1, 7, 14 and 21, and subsequent OVA… CONTINUE READING

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