Bone marrow-derived endothelial progenitor cells and endothelial cells may contribute to endothelial repair in the kidney immediately after ischemia-reperfusion.

@article{Kwon2010BoneME,
  title={Bone marrow-derived endothelial progenitor cells and endothelial cells may contribute to endothelial repair in the kidney immediately after ischemia-reperfusion.},
  author={Osun Kwon and Shane Miller and Nan Li and Akhtar Khan and Zakiyah Kadry and Tadahiro Uemura},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  year={2010},
  volume={58 8},
  pages={687-94}
}
In ischemic acute kidney injury, renal blood flow is decreased. We have previously shown that reperfused, transplanted kidneys exhibited ischemic injury to vascular endothelium and that preservation of peritubular capillary endothelial integrity may be critical to recovery from ischemic injury. We hypothesized that bone marrow-derived (BMD) endothelial progenitor cells (EPCs) might play an important role in renal functional recovery after ischemia. We tested this hypothesis in recipients of… CONTINUE READING
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