Bone marrow characterization in COPD: a multi-level network analysis

  title={Bone marrow characterization in COPD: a multi-level network analysis},
  author={Nuria Toledo-Pons and G. Noell and A. Jahn and A. Iglesias and M. A. Dur{\'a}n and Julio F. Iglesias and Angel R{\'i}os and Sergio Scrimini and R. Faner and Orlando Gigirey and A. Agusti and B. Cos{\'i}o},
  journal={Respiratory Research},
  • Nuria Toledo-Pons, G. Noell, +9 authors B. Cosío
  • Published 2018
  • Medicine
  • Respiratory Research
  • BackgroundBone marrow (BM) produces hematopoietic and progenitor cells that contribute to distant organ inflammation and repair. Chronic obstructive pulmonary disease (COPD) is characterized by defective lung repair. Yet, BM composition has not been previously characterized in COPD patients.MethodsIn this prospective and controlled study, BM was obtained by sternum fine-needle aspiration in 35 COPD patients and 25 healthy controls (10 smokers and 15 never-smokers). BM cell count and… CONTINUE READING
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