Bone marrow cells transdifferentiate to cardiomyocytes when introduced into the embryonic heart.


Since rates of cardiomyocyte generation in the embryo are much higher than within the adult, we explored whether the embryonic heart would serve as useful experimental system for examining the myocardial potential of adult stem cells. Previously, we reported that the long-term culturing of adult mouse bone marrow produced a cell population that was both… (More)


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