Bone marrow aplasia induced by passenger leukocytes from heart allografts.

@article{Ko2001BoneMA,
  title={Bone marrow aplasia induced by passenger leukocytes from heart allografts.},
  author={Saiho Ko and Marc Hendrik Dahlke and Oliver S Lauth and Mark D J{\"a}ger and Andrea Deiwick and Astrid Dinkel and T Y Tsui and Kurt Wonigeit and Hans J. Schlitt},
  journal={Experimental hematology},
  year={2001},
  volume={29 3},
  pages={339-44}
}
OBJECTIVE Organ allografts contain passenger leukocytes that are transferred to the recipient with the transplantation, but their functional relevance to the recipient's immune system is still controversial. MATERIALS AND METHODS To clarify the functional capacity of passenger leukocytes, we attempted to enhance their effect in rat heart allograft recipients by selective depletion of recipient leukocytes using a monoclonal antibody (mAb) against a recipient-specific allotype of CD45 (RT7(a… CONTINUE READING