Bone marrow angiogenesis in 400 patients with monoclonal gammopathy of undetermined significance, multiple myeloma, and primary amyloidosis.

@article{Rajkumar2002BoneMA,
  title={Bone marrow angiogenesis in 400 patients with monoclonal gammopathy of undetermined significance, multiple myeloma, and primary amyloidosis.},
  author={S Vincent Rajkumar and Ruben A. Mesa and Rafael Luı́s Fonseca and G. Schr{\"o}der and Matthew F. Plevak and Angela Dispenzieri and Martha Q. Lacy and John A. Lust and Thomas E Witzig and Morie A Gertz and Robert A Kyle and Stephen Russell and Philip R. Greipp},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2002},
  volume={8 7},
  pages={2210-6}
}
PURPOSE To determine whether bone marrow (BM) angiogenesis progressively increases along the spectrum of plasma cell disorders ranging from monoclonal gammopathy of undetermined significance (MGUS) to advanced myeloma. EXPERIMENTAL DESIGN Four hundred patients with the following disorders were studied: MGUS (76 patients); smoldering (indolent; early-stage) multiple myeloma (SMM; 112 patients); newly diagnosed, active multiple myeloma (MM; 99 patients); relapsed (advanced) multiple myeloma… CONTINUE READING