Bone manganese as a biomarker of manganese exposure: a feasibility study.

  title={Bone manganese as a biomarker of manganese exposure: a feasibility study.},
  author={Ana Pejovi{\'c}-Mili{\'c} and David R. Chettle and John D Oudyk and Michael W Pysklywec and Ted Haines},
  journal={American journal of industrial medicine},
  volume={52 10},
BACKGROUND There is a need for a diagnostic tool with the ability to measure cumulative exposure to manganese (Mn) in the workplace. Measuring bone Mn levels with in vivo neutron activation analysis (IVNAA) could serve as a biomarker of past exposure. Bone Mn levels of welders were measured and compared to the levels found in subjects without exposure to the element. METHOD Forty subjects (30 welders and 10 controls) were recruited. An occupational history was obtained and subjects underwent… CONTINUE READING

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