Bone involvement in sickle cell disease

@article{Almeida2005BoneII,
  title={Bone involvement in sickle cell disease},
  author={A. Almeida and I. Roberts},
  journal={British Journal of Haematology},
  year={2005},
  volume={129}
}
Bone involvement is the commonest clinical manifestation of sickle cell disease both in the acute setting such as painful vaso‐occlusive crises, and as a source of chronic, progressive disability such as avascular necrosis. Management of these problems is often difficult because of the diagnostic imprecision of most laboratory and imaging investigations and because of the lack of evidence for most surgical procedures in sickle cell disease. This review first discusses the acute problems related… Expand
Imaging of musculoskeletal manifestations in sickle cell disease patients.
TLDR
The pathophysiology and key imaging findings related to these complications are reviewed and awareness and knowledge of the imaging features related toThese complications are essential for early diagnosis and prompt management. Expand
Management of Osteomyelitis in Sickle Cell Disease: Review Article
TLDR
Treatment of osteomyelitis in patients with SCD may be medical or surgical, but considerations in antibiotic selection and management preoperatively and postoperatively must be taken to ensure optimal outcomes. Expand
Osteoarticular involvement in sickle cell disease
TLDR
More detailed studies are required to understand the pathophysiological mechanisms involved in the complications of sickle cell disease and propose more adequate and specific therapies. Expand
Idiopathic facial swelling secondary to sickle cell anaemia
TLDR
A case of idiopathic facial swelling associated with sickle cell disease in a young patient is described. Expand
The Evaluation of Bilateral Femoral Head Osteonecrosis Secondary to Sickle Cell Anemia Crisiswith Bone Scintigraphy
TLDR
A 29 year old male patient who has sickle cell anemia and who has been experiencing pain and difficulty in walking for a month is chosen. Expand
Musculoskeletal of Sickle Cell Disease 1
TLDR
The clinical and radiographic features of acute osteomyelitis may be particularly difficult to distinguish from those of bone infarction; therefore, care must be taken to achieve an accurate diagnosis by identifying or excluding bone involvement. Expand
Musculoskeletal manifestations of sickle cell disease.
TLDR
The clinical and radiographic features of acute osteomyelitis may be particularly difficult to distinguish from those of bone infarction; therefore, care must be taken to achieve an accurate diagnosis by identifying or excluding bone involvement. Expand
Dactylitis: A Complication in Patients With Sickle Cell Disease
Sickle cell disease (SCD) is a group of disorders that affects hemoglobin, the red pigment in blood erythrocytes responsible for delivering oxygen throughout the body. This is the most commonlyExpand
Musculoskeletal Manifestations of Sickle Cell Anaemia: A Pictorial Review
TLDR
The various musculoskeletal manifestations of sickle cell disease are discussed and illustrated focusing primarily on marrow hyperplasia, osteomyelitis and septic arthritis, medullary and epiphyseal bone infarcts, growth defects, and soft tissue changes. Expand
Osteoarticular complications of sickle cell disease in children
TLDR
The osteoarticular complications must be hunted in children with sickle cell disease in order to diagnose them early and avoid serious orthopaedic sequela. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 99 REFERENCES
Osteoarticular disorders of haematological origin.
Clinical abnormalities of the musculoskeletal system may be the first manifestation of sickle haemoglobinopathies, leukaemias, lymphomas and haemophilia. In addition to this, known patients withExpand
Bone disorders in sickle-cell disease
  • O. Onuba
  • Medicine
  • International Orthopaedics
  • 2004
SummarySickle cell disease involves many organs but musculo-skeletal problems present most often with bone pain, the most common reason for admission to hospital. Two separate pathologicalExpand
Vertebral bone destruction in sickle cell disease: infection, infarction or both.
Infectious and vaso-occlusive vertebral bone and joint destruction in two patients with sickle cell disease (SCD) are featured by H-shaped vertebrae, kyphotic angulation, osteolysis of endplates andExpand
Acute infarction of long bones in children with sickle cell anemia.
TLDR
Records from 192 children with sickle hemoglobinopathies were reviewed and 41 episodes of acute long bone infarction were identified, with the most commonly affected bones being the humerus, tibia, and femur. Expand
Osteomyelitis in children with sickle cell disease: early diagnosis with contrast-enhanced CT.
TLDR
Two children with sickle cell disease and osteomyelitis were treated and definitive treatment was delayed until computed tomography (CT) revealed a subperiosteal abscess, which resulted in prompt diagnosis and treatment. Expand
Mandibular lesions of vasoocclusive origin in sickle cell hemoglobinopathy
TLDR
In conclusion, vasoocclusive involvement should be taken into consideration when assessing painful episodes or neurological symptoms in the maxillofacial region in this patient population. Expand
Sickle cell disease and silent avascular necrosis of the hip.
We reviewed the prevalence of avascular necrosis (AVN) in a series of patients with sickle cell disease, using radiography and magnetic resonance imaging. We found AVN of at least one hip in 11 of 27Expand
Sickle cell disease with orbital infarction and epidural hematoma
TLDR
Imaging findings are reported in a 16-year-old boy with sickle cell disease with orbital infarction and epidural hematoma, probably related to vaso-occlusive episodes and the tearing of small vessels. Expand
Septic arthritis in patients with sickle-cell disease.
TLDR
The presenting features, modes of treatment and sequelae of septic arthritis of 50 joints in 31 Nigerians with sickle-cell disease were studied prospectively over a 66-month period, and severe complications occurred in 76%, apparently due to delay in diagnosis, severity of illness and a high incidence of hip-joint infection. Expand
Sickle cell dactylitis: histopathologic observations.
TLDR
The histopathologic features of Sickle cell dactylitis observed at autopsy in a 9-month-old Negro infant with sickle cell disease (homozygous S) are described and are similar to those observed in experimental models in which the medullary blood supply is completely interrupted with sparing of the periosteal vascular bed. Expand
...
1
2
3
4
5
...