Bone geometry and strength are adapted to muscle force in children and adolescents perinatally infected with HIV.

@article{Macdonald2013BoneGA,
  title={Bone geometry and strength are adapted to muscle force in children and adolescents perinatally infected with HIV.},
  author={Heather Macdonald Macdonald and Jian-jun Chu and Lindsay A Nettlefold and Evelyn J Maan and John C. Forbes and H{\'e}l{\`e}ne C F C{\^o}t{\'e} and Ariane Alimenti},
  journal={Journal of musculoskeletal & neuronal interactions},
  year={2013},
  volume={13 1},
  pages={
          53-65
        }
}
OBJECTIVES To determine if bone health is compromised in perinatally HIV-infected youth. METHODS We assessed BMC at the proximal femur, lumbar spine and total body using DXA in perinatally HIV-infected youth (n=31; 9-18y). Using pQCT, we assessed muscle CSA, total and cortical bone area, cortical BMD and thickness and strength strain index at the tibial shaft. Thirty and 18 participants returned at 12- and 24-months, respectively. We calculated age- and sex-specific z-scores for the HIV… CONTINUE READING

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