Bone formation analysis: effect of quantification procedures on the study outcome.

@article{LopezHeredia2012BoneFA,
  title={Bone formation analysis: effect of quantification procedures on the study outcome.},
  author={Marco Antonio Lopez-Heredia and Matilde Bongio and Vincent M. J. I. Cuijpers and Natasja W M van Dijk and Jeroen J. J. P. van den Beucken and Joop G. C. Wolke and John A. Jansen},
  journal={Tissue engineering. Part C, Methods},
  year={2012},
  volume={18 5},
  pages={369-73}
}
Quantification of the amount of newly formed bone is an essential part of bone regeneration studies. Histomorphometry, based on histological sections of plastic-embedded specimens, is the most frequently applied technique in this assessment. Before performing image analysis, a specific region of interest (ROI) has to be determined. Based on the histological… CONTINUE READING