Bone disorders in spontaneously hypertensive rat

  title={Bone disorders in spontaneously hypertensive rat},
  author={Yoshihiro Izawa and Kiyoshi Sagara and Takashi Kadota and Tokutaro Makita},
  journal={Calcified Tissue International},
The bones of adult (26 weeks old) spontaneously hypertensive rats (SHR) were examined chemically and histologically by comparing them with those of the corresponding normotensive Wistar-Kyoto (WKY) rats. The mean cortical thickness, the mean ash weight per unit bone volume, and the ash as percentage of dry weight of femur were significantly lower in SHR than in WKY. Besides, the percent cortical area measured on tibial cross-section was also reduced in SHR compared with WKY. These findings… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 29 extracted citations


Publications referenced by this paper.
Showing 1-7 of 7 references

Abnormal bone density in the spontaneously hypertensive rat: differential effect of dietary sodium and calcium

  • J Metz, N Karanja, DA McCarron
  • Proc Am Soc Nephrol 17:24A
  • 1984
1 Excerpt

Bone his tomorphometry : image analysis

  • T Konno, H Takahashi
  • 1983

Bone his tomorphometry: image analysis. In: Takahashi H (ed) Handbook of bone morphometry

  • T Konno, H Takahashi
  • 1983
1 Excerpt

Similar Papers

Loading similar papers…