Bone development.

  title={Bone development.},
  author={Bj{\"o}rn Reino Olsen and Anthony M. Reginato and Wen-Der Wang},
  journal={Annual review of cell and developmental biology},
Early development of the vertebrate skeleton depends on genes that pattern the distribution and proliferation of cells from cranial neural crest, sclerotomes, and lateral plate mesoderm into mesenchymal condensations at sites of future skeletal elements. Within these condensations, cells differentiate to chondrocytes or osteoblasts and form cartilages and bones under the control of various transcription factors. In most of the skeleton, organogenesis results in cartilage models of future bones… CONTINUE READING
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