Bone density and shape as determinants of bone strength in IGF-I and/or pamidronate-treated ovariectomized rats

@article{Ammann1996BoneDA,
  title={Bone density and shape as determinants of bone strength in IGF-I and/or pamidronate-treated ovariectomized rats},
  author={Dr P. Ammann and Ren{\'e} R Rizzoli and Josefin Meyer and J. -P. Bonjour},
  journal={Osteoporosis International},
  year={1996},
  volume={6},
  pages={219-227}
}
Areal bone mineral density (BMD) is a major determinant of bone strength and thereby of fracture risk. Other factors including trabecular microarchitecture and bone dimensions also contribute to bone strength. To investigate the relative importance for bone strength of BMD and bone dimensions, the relations between strength and the latter variables were evaluated under different experimental conditions in ovariectomized rats. Bone strength was assessed in compression and bending with… CONTINUE READING
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