Bone chondroadherin promotes attachment of osteoblastic cells to solid-state substrates and shows affinity to collagen

@article{Mizuno1996BoneCP,
  title={Bone chondroadherin promotes attachment of osteoblastic cells to solid-state substrates and shows affinity to collagen},
  author={Morimichi Mizuno and Ryuichi Fujisawa and Yoshinori Kuboki},
  journal={Calcified Tissue International},
  year={1996},
  volume={59},
  pages={163-167}
}
Chondroadherin, which is reported to be synthesized by chondrocytes and to promote their attachment, was purified from bovine bone. It was a minor component of bone organic matrix, and was present in the 4 M guanidine extract of demineralized bone. Chondroadherin promoted attachment of osteoblastic cells to solid-state substrates, and bound to collagen. Binding of chondroadherin to collagen was significantly higher than that of osteonectin or decorin. These findings imply that chondroadherin… CONTINUE READING

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The structure of a 38-kDa leucine-rich protein (chondroadherin) isolated from bovine cartilage

  • PJ Naeme, Y Sommarin, RE Boynton
  • HeinegArd
  • 1994
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