Bone Tissue Engineering with Multilayered Scaffolds-Part I: An Approach for Vascularizing Engineered Constructs In Vivo.

@article{Sathy2015BoneTE,
  title={Bone Tissue Engineering with Multilayered Scaffolds-Part I: An Approach for Vascularizing Engineered Constructs In Vivo.},
  author={Binulal Nelson Sathy and Ullas Mony and Deepthy Menon and Vasudevan Baskaran and Antonios G Mikos and Shantikumar Vasudevan Nair},
  journal={Tissue engineering. Part A},
  year={2015},
  volume={21 19-20},
  pages={2480-94}
}
Obtaining functional capillaries through the bulk has been identified as a major challenge in tissue engineering, particularly for critical-sized defects. In the present study, a multilayered scaffold system was developed for bone tissue regeneration, designed for through-the-thickness vascularization of the construct. The basic principle of this approach was to alternately layer mesenchymal stem cell-seeded nanofibers (osteogenic layer) with microfibers or porous ceramics (osteoconductive… CONTINUE READING

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Bone tissue engineering with multi-layered scaffolds-Part II: Combining Page

  • N. S. Binulal, B. M. Watson, +4 authors S. Nair
  • 2014

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