Bone Remodeling

  title={Bone Remodeling},
  author={D. Hadjidakis and I. Androulakis},
  journal={Annals of the New York Academy of Sciences},
  • D. Hadjidakis, I. Androulakis
  • Published 2006
  • Medicine
  • Annals of the New York Academy of Sciences
  • Abstract:  The skeleton is a metabolically active organ that undergoes continuous remodeling throughout life. Bone remodeling involves the removal of mineralized bone by osteoclasts followed by the formation of bone matrix through the osteoblasts that subsequently become mineralized. The remodeling cycle consists of three consecutive phases: resorption, during which osteoclasts digest old bone; reversal, when mononuclear cells appear on the bone surface; and formation, when osteoblasts lay down… CONTINUE READING
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