Bone Mineral Density and Body Composition in Underweight and Normal Elderly Subjects

  title={Bone Mineral Density and Body Composition in Underweight and Normal Elderly Subjects
  author={Alessandra Coin and Giuseppe Sergi and P. Beninc{\`a} and Lucia Lupoli and Giovanni Cinti and L. Ferrara and Gracia Benedetti and Giovanna Tomasi and Claudia Pisent and Giuliano Enzi},
  journal={Osteoporosis International},
Abstract: The importance of malnutrition as a risk factor in osteoporosis is emphasized by the evidence that patients with fractures of the proximal femur are often undernourished. In this study, nutritional status, bone mineral mass and its association with body composition were investigated in underweight and normal weight elderly subjects. Moreover the hypothesis that malnutrition in elderly is associated with a higher risk of osteoporosis was tested. The participants were 111 elderly… 
Predictors of low bone mineral density in the elderly: the role of dietary intake, nutritional status and sarcopenia
BMI in both genders, albumin in women and protein intake in men have an independent effect on BMD, and age-related sarcopenia does not seem to be involved in bone mass loss.
Body composition in older men is positively associated with BMD at all body sites (arms, legs, and trunk) and higher age was associated with poorer BMD.
Biochemical Markers of Nutrition and Bone Mineral Density in the Elderly
The results support the role of protein nutrition in bone health, at least in elderly frail patients and TLC and serum albumin were suitable markers, however sex-related differences in their usefulness were observed.
Serum Albumin and Bone Mineral Density in Healthy Men above 30 Years Old
Serum albumin level was significantly increased as increasing BMD of L-spine, femoral neck and the correlation between serum albumin and BMD were positively correlated, indicating prevention and treatment of osteoporosis.
Relationship between body composition and bone mineral density in women with and without osteoporosis: relative contribution of lean and fat mass
It is indicated that both TFM and TLM affect bone density, with different physiological/pathological conditions modulating this relationship.
Association between lean mass and handgrip strength with bone mineral density in physically active postmenopausal women.
Relation between body composition and bone mineral density in young undregraduate students with different nutritional status
Total body and segmental body fat were correlated with bone mineral density and bone mineral content in male undergraduate students, particularly in overweight individuals.
Predictors of low bone mineral density in elderly males with chronic obstructive pulmonary disease: the role of body mass index
  • A. CoinG. Sergi E. Manzato
  • Medicine
    The aging male : the official journal of the International Society for the Study of the Aging Male
  • 2010
In elderly males with COPD, the BMI values are more strongly related to low BMD levels than albumin values, and BMI values within the normal range for younger adults might point out a higher risk of osteoporosis.
BMI, hypertension and low bone mineral density in adult men and women.


Relation between body size and bone mineral density in elderly men and women.
In this cohort, all measures of body size were associated with bone mineral density in both sexes and were better markers of bone mineraldensity in the weight-bearing sites than in the non-weight- bearing sites, implying a mechanical effect of weight on bone Mineral density.
Bone mineral density in elderly men and women: results from the Framingham osteoporosis study.
  • M. HannanD. FelsonJ. Anderson
  • Medicine
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
  • 1992
Bone mass and body composition in normal women.
Bone mass, lean mass, and fat mass: same genes or same environments?
It is concluded that lean mass andfat mass, as well as bone density, are under strong genetic regulation, however, the associations between BMD and fat mass or betweenLean mass andFat mass appear to be mediated mainly via environmental influences.
Serum albumin is associated with skeletal muscle in elderly men and women.
Serum albumin concentrations decrease with age and values < 38 g/L are associated with increased morbidity, mortality, and disability in the elderly. It is not clear to what extent the decreases are
To what extent is bone mass determined by fat-free or fat mass?
In black and white healthy women, although bone mass may be partially influenced by fatness or race, the major determinant of bone mass is FFM, and fat mass may play a more important role in postmenopausal women.
Advantage of knee height over height as an index of stature in expression of body composition in adults.
The ability of height and knee height indexes to correctly describe the loss of FFM seen with increasing age between 28 and 75 y is examined and suggests that knee height is a reliable surrogate for stature and should be used to adjust body composition measurements when bioimpedance is used to estimate body composition.
Uncritical use of bone mineral density in absorptiometry may lead to size-related artifacts in the identification of bone mineral determinants.
A general approach to size adjustment is described, in which BA (BW), weight, and height are incorporated in all regression models of BMC, and it is advocated that its use in epidemiological research be discontinued.
Height-normalized indices of the body's fat-free mass and fat mass: potentially useful indicators of nutritional status.
These findings indicate that FFMI and BFMI may be useful in nutritional assessment, and use of height-normalized indices, namely, a FFM index and a BFM index, together with basal oxygen-consumption rate, diagnosed PEM in 27 of the 32 Minnesota Study subjects after 12 wk of semi-starvation.
Appendicular skeletal muscle mass: measurement by dual-photon absorptiometry.
Appendicular skeletal muscle mass estimated by DPA is thus a potentially practical and accurate method of quantifying human skeletal Muscle mass in vivo.