Bone Metastasis of Glioblastoma Multiforme Confirmed by Fine Needle Biopsy

  title={Bone Metastasis of Glioblastoma Multiforme Confirmed by Fine Needle Biopsy},
  author={D. Frappaz and F. Mornex and G. Saint-Pierre and D. Ranch{\`e}re‐Vince and A. Jouvet and C. Chassagne-Cl{\'e}ment and P. Thiesse and P. M{\'e}r{\'e} and R. Deruty},
  journal={Acta Neurochirurgica},
  • D. Frappaz, F. Mornex, +6 authors R. Deruty
  • Published 1999
  • Medicine
  • Acta Neurochirurgica
  • After standard treatment of glioblastoma multiforme (GM) using surgery and focal radiation therapy, a loco-regional relapse, and ultimately death usually occur within two years. Some reports of spinal metastases suggest that spreading in the neuraxis might ultimately occur if local treatment was always successful. The occurrence of metastases outside the neuraxis is rare and suggests that GM may have the ability to form metastases as any cancer. Histological documentation before autospy is rare… CONTINUE READING
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