Bone Marrow as a Source of Cells for Paroxysmal Nocturnal Hemoglobinuria Detection.

@article{DulauFlorea2018BoneMA,
  title={Bone Marrow as a Source of Cells for Paroxysmal Nocturnal Hemoglobinuria Detection.},
  author={Alina E Dulau-Florea and Neal S. Young and Irina Maric and Katherine R Calvo and Cynthia E Dunbar and Danielle M. Townsley and Thomas Winkler and Mariela Monreal and Chunjie Jiang and Elaine Kay Jordan and Raul C. Braylan},
  journal={American journal of clinical pathology},
  year={2018}
}
Objectives To determine fluorescently labeled aerolysin (FLAER) binding and glycophosphatidylinositol-anchored protein expression in bone marrow (BM) cells of healthy volunteers and patients with paroxysmal nocturnal hemoglobinuria (PNH) detected in peripheral blood (PB); compare PNH clone size in BM and PB; and detect PNH in BM by commonly used antibodies… CONTINUE READING