Bone Marrow Stem Cell Chemotactic Activity Is Induced by Elevated CXCl12 in Endometriosis.

@article{Moridi2017BoneMS,
  title={Bone Marrow Stem Cell Chemotactic Activity Is Induced by Elevated CXCl12 in Endometriosis.},
  author={Irene Moridi and Ramanaiah Mamillapalli and Emine Coşar and Gulcin Sahin Ersoy and Hugh S. Taylor},
  journal={Reproductive sciences},
  year={2017},
  volume={24 4},
  pages={526-533}
}
Endometriosis is an inflammatory gynecological disorder caused by the growth of endometrial tissue outside the uterus. Endometriosis produces chemokines, including CXCL12, that attract bone marrow cells to the lesions. In this study, we describe the expression, localization, and chemotactic activity of CXCL12 in endometriotic lesions. Biopsies were collected both from women with endometriosis undergoing laparoscopy and control endometrium from women without endometriosis. Expression of CXCl12… CONTINUE READING

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