Bone Marrow Microenvironment in Multiple Myeloma Progression


Substantial advances have been made in understanding the biology of multiple myeloma (MM) through the study of the bone marrow (BM) microenvironment. Indeed, the BM niche appears to play an important role in differentiation, migration, proliferation, survival, and drug resistance of the malignant plasma cells. The BM niche is composed of a cellular… (More)
DOI: 10.1155/2012/157496