Bone Engineering of Maxillary Sinus Bone Deficiencies Using Enriched CD90+ Stem Cell Therapy: A Randomized Clinical Trial.

@article{Kaigler2015BoneEO,
  title={Bone Engineering of Maxillary Sinus Bone Deficiencies Using Enriched CD90+ Stem Cell Therapy: A Randomized Clinical Trial.},
  author={Darnell Kaigler and Gustavo Avila-Ortiz and Suncica Travan and Andrei Dan Taut and Miguel Padial-Molina and Ivan Elimar Rudek and Feng Wang and Alejandro Lanis and William V Giannobile},
  journal={Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research},
  year={2015},
  volume={30 7},
  pages={1206-16}
}
Bone engineering of localized craniofacial osseous defects or deficiencies by stem cell therapy offers strong prospects to improve treatment predictability for patient care. The aim of this phase 1/2 randomized, controlled clinical trial was to evaluate reconstruction of bone deficiencies of the maxillary sinus with transplantation of autologous cells enriched with CD90+ stem cells and CD14+ monocytes. Thirty human participants requiring bone augmentation of the maxillary sinus were enrolled… CONTINUE READING
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