Bombesin-like peptides stimulate somatostatin release from rat fundic D cells in primary culture.

Abstract

In several species, bombesin-like neuropeptides stimulate somatostatin release in in vitro preparations of gastric mucosa. We sought to determine if this response is due to a direct effect on fundic D cells. Rat fundic mucosal cells were isolated by pronase E (1% D cells). D cells were separated by counterflow elutriation and subsequent density-gradient… (More)

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@article{Schaffer1997BombesinlikePS, title={Bombesin-like peptides stimulate somatostatin release from rat fundic D cells in primary culture.}, author={Kate Schaffer and H Herrmuth and Julia Mueller and David H. Coy and H. Chi Wong and J. H. Tull Walsh and Meinhard Classen and Volker Schusdziarra and Wolfgang Schepp}, journal={The American journal of physiology}, year={1997}, volume={273 3 Pt 1}, pages={G686-95} }